From clarinet notes to critical care: dual antifungal therapy in an immunocompetent patient with a diagnosis of invasive pulmonary aspergilosis. Case report
From clarinet notes to critical care: dual antifungal therapy in an immunocompetent patient with a diagnosis of invasive pulmonary aspergilosis. Case report
Mercedes Carrasco-Sánchez 1, Javier Carrillo-Hernández-Rubio 1, Estefanía Llopis-Pastor 1, Mercedes García-Salmones-Martín 2
1 Servicio de Neumología, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, Spain; 2 Servicio de Neumología; Unidad de Neumología Intervencionista; 3Servicio de Anatomía Patológica. Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, España
Mercedes Carrasco-Sánchez, Javier Carrillo-Hernández-Rubio, Estefanía Llopis-Pastor, Mercedes García-Salmones-Martín
La información completa de afiliaciones y autor de correspondencia está disponible en la versión original en PDF.
*Correspondence: Estefanía Llopis-Pastor, Email not available
Summary
Invasive pulmonary aspergillosis is a severe fungal infection, typically associated with immunocompromised patients. An atypical case of invasive pulmonary aspergillosis is presented in a 65-year-old immunocompetent patient, a smoker, and a clarinetist. Treatment involved the administration of intravenous antifungals (voriconazole and amphotericin B) and nebulized therapy (amphotericin B). Additionally, hypersensitivity pneumonitis related to continuous exposure to Aspergillus fumigatus during clarinet practice was identified. This case underscores the uniqueness of invasive pulmonary aspergillosis in non-immunocompromised patients and emphasises the necessity for therapeutic approaches tailored to exceptional clinical circumstances.
Keywords: Invasive pulmonary aspergillosis. Voriconazole. Amphotericin B. Hypersensitivity pneumonitis.
